Enjoy fishing, hiking, biking, hunting, winery tours/tastings (watch your BAC), Daniel Boone’s grave; German architecture, museums, and furniture.
U.S. 61 to Herman is a trip through the center of Missouri wine country west of St. Louis. The drive begins at the August A. Busch Memorial Conservation Area, which offers more than 16,000 acres of fishing, hunting, biking, and hiking. Drive west on Route 94 toward Defiance. A 5-mile drive on Route F will take you to the Daniel Boone House. Returning to Route 94, you will see the 200-mile KATY Trail for hiking and biking. Get in wine country west of Defiance.
Many wineries are along this path, and all offer tastings and tours. The world’s only corncob-pipe plant is 4 miles south of Dutzow, in the town of Washington. The town Read more . . .
The drive from Salem to Eminence on Route 19 is a 44-mile, 1-hour travel and is best driven in the spring through fall. The tour winds through farm country and upland forests. You will see lots of gorgeous panorama everywhere along this drive, as you slice through a small portion of the Ozarks. As you travel south from Salem on Route 19, several side streets will take you into parts of the gigantic, 1.5 million-acre Mark Twain National Forest. Route 19 climbs the Ozark Plateau on its way to the Current River and its southern stream, the Jacks Fork River, part of the Ozark National Scenic Riverways. 
Duluth may not be everyone’s idea of a perfect vacation destination, but it’s a great starting point for this spectacular experience in Minnesota’s North Country. You can head out along the rugged Lake Superior coast on Route 61 where rocky shores, lighthouses, waterfalls, and steep cliffs cause you to consciously pull your eyes away from the scenery to watch the road.
The Great River Road (GRR) stars in Lake Itasca State Park, Minnesota. Driving through Minnesota on the GRR takes you past the northern boreal forest, hayfields and tree farms, running along the Mississippi River. Farther south, the Big-tooth Aspen, the Red and White pines, and Paper Birch fade away as more and more farms make up the scenery.
This 27-mile picturesque drive through part of the Keweenaw Peninsula offers the beauty of the Michigan countryside and the luxury of an all-weather, well-maintained and black-topped highway. Starting in the town of Phoenix, this gorgeous stretch of U.S. 41 takes you through a number of recreational, natural, historic, and scenic sites. Along this route you will find an underground copper mine tour, an original 1850s General Store, and two roadside parks that offer a nice perching area for viewing the wonderful surroundings.