Visit bluffs, hiking, camping, fishing, scenic river drives, canoeing, wildlife, limestone bluffs and rocky uplands, and traditional “unprettified” small towns.
Although maybe not for everyone, a trip of the Great River Road (GRR) offers much compared to the average interstate. It changes route frequently, crossing the Mississippi River when it can, and dallying in towns all other roads have forgotten. Driving the GRR, road trippers can escape creeping RVs, semi trucks, and endless billboards usually found on other routes. Other rewards include wildlife and local color.
The Great River Road was created in 1938 from a network of state, federal, and local roads. The drive (also famous as the River Road) forms a single route along the Mississippi. Showing off the 10 states
bordering the Read more . . .
Killdeer to New Town on Route 22 is about 95 miles and takes 2 hours, that is, if you don’t stop. Starting in Killdeer, head north on Route 22 to the Killdeer Battlefield State Historic Site. In 1864 (July 28) , it was at this location that a battle was fought between troops commanded by General Alfred Sully and the Sioux Indians. General Sully’s 2,200 troops, with the help of artillery batteries, destroyed the Sioux Indian village with a reported 6,000 warriors. Sully lost 5 soldiers with Sioux losses totaling between 100-150 Native Americans; there is a symbol on the location. 
The drive from Salem to Eminence on Route 19 is a 44-mile, 1-hour travel and is best driven in the spring through fall. The tour winds through farm country and upland forests. You will see lots of gorgeous panorama everywhere along this drive, as you slice through a small portion of the Ozarks. As you travel south from Salem on Route 19, several side streets will take you into parts of the gigantic, 1.5 million-acre Mark Twain National Forest. Route 19 climbs the Ozark Plateau on its way to the Current River and its southern stream, the Jacks Fork River, part of the Ozark National Scenic Riverways.